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Daxx Rabbit mAb

Anti-Daxx Rabbit Monoclonal Antibody
5/5

¥2,850.00

货号:N263297

规格: 100 微升

库存状态:In Stock

           产品描述          
货号:   N263297
产品全名:   Daxx 兔单克隆抗体
基因符号   DAXX; BING2; DAP6; Death domain-associated protein 6; Daxx; hDaxx; ETS1-associated protein 1; EAP1; Fas death domain-associated 蛋白
UNIPROT ID:   Q9UER7
背景:   Acts as an adapter protein in a MDM2-DAXX-USP7 complex by regulating the RING-finger E3 ligase MDM2 ubiquitination activity. Under non-stress condition, in association with the deubiquitinating USP7, prevents MDM2 self-ubiquitination and enhances the intrinsic E3 ligase activity of MDM2 towards TP53, thereby promoting TP53 ubiquitination and subsequent proteasomal degradation. Upon DNA damage, its association with MDM2 and USP7 is disrupted.
抗原:   A synthetic peptide of human Daxx
经过测试的应用:   WB,ICC/IF
推荐稀释比:   WB: 1/500-1/1000 IF: 1/50-1/200
种属反应性:   Rabbit
克隆性:   Rabbit Monoclonal
克隆编号:   R07-7F4
分子量:   Calculated MW: 81 kDa; Observed MW: 110 kDa
亚型:   IgG
纯化:   Affinity Purified
种属反应性:   Human
成分:   PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide
研究领域:   Cell Biology
储存和运输:   Store at -20°C. Avoid repeated freezing and thawing

Western blot analysis of Daxx in HepG2, U251, HL-60 lysates using Daxx antibody.

Immunocytochemistry analysis of Daxx (green) in K562 using Daxx antibody,and DAPI(blue).
           引用文献