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Phospho-BRAF (Thr401) Rabbit pAb

Anti-Phospho-BRAF (Thr401) Rabbit Polyclonal Antibody
5/5

¥2,850.00

货号:N225743

规格: 100 微升

库存状态:In Stock

           产品描述          
货号:   N225743
产品全名:   Phospho-BRAF (Thr401) 兔多抗
基因符号   BRAF; BRAF1; RAFB1; Serine/threonine-protein kinase B-raf; Proto-oncogene B-Raf; p94; v-Raf murine sarcoma viral oncogene homolog B1
UNIPROT ID:   P15056
背景:   Involved in the transduction of mitogenic signals from the cell membrane to the nucleus. May play a role in the postsynaptic responses of hippocampal neuron. Frequently mutated in thyroid cancers, skin melanomas and at lower frequency in a wide range of human cancers. An activating mutation, mimicking phosphorylation of the activation loop, is seen in 60% of malignant melanoma samples. Raf mutations are generally exclusive to Ras activating mutations.
抗原:   A synthesized peptide derived from human Phospho-B Raf (T401)
经过测试的应用:   WB,ICC/IF,IP
推荐稀释比:   WB: 1/500-1/1000 IF: 1/50-1/200 IP: 1/20
种属反应性:   Rabbit
克隆性:   Rabbit Polyclonal
分子量:   Calculated MW: 84 kDa; Observed MW: 84 kDa
亚型:   IgG
纯化:   Affinity Chromatography
种属反应性:   Human, Mouse and Rat
Modification:   Phosphorylated
成分:   PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide
研究领域:   Cell Biology
储存和运输:   Store at -20°C. Avoid repeated freezing and thawing

Western blot analysis of Phospho-B Raf (T401) in (1) PC-12 lysates; (2) PC-12 lysates treated with TPA using Phospho-BRAF (Thr401) antibody.
           引用文献