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YBX1 Rabbit pAb

Anti-YBX1 Rabbit Polyclonal Antibody
5/5

¥2,850.00

货号:S221531

规格: 100 微升

库存状态:In Stock

           产品描述          
货号:   S221531
产品全名:   YBX1 兔多抗
基因符号   YB1; BP-8; CSDB; DBPB; YB-1; CBF-A; CSDA2; EFI-A; NSEP1; NSEP-1; MDR-NF1
UNIPROT ID:   P67809 (Gene Accession – NP_004550 )
背景:   This gene encodes a highly conserved cold shock domain protein that has broad nucleic acid binding properties. The encoded protein functions as both a DNA and RNA binding protein and has been implicated in numerous cellular processes including regulation of transcription and translation, pre-mRNA splicing, DNA reparation and mRNA packaging. This protein is also a component of messenger ribonucleoprotein (mRNP) complexes and may have a role in microRNA processing. This protein can be secreted through non-classical pathways and functions as an extracellular mitogen. Aberrant expression of the gene is associated with cancer proliferation in numerous tissues. This gene may be a prognostic marker for poor outcome and drug resistance in certain cancers. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on multiple chromosomes.
抗原:   Synthetic peptide of human YBX1
经过测试的应用:   ELISA, IHC
推荐稀释比:   IHC: 20-100; ELISA: 5000-10000
种属反应性:   Rabbit
克隆性:   Rabbit Polyclonal
亚型:   Immunogen-specific rabbit IgG
纯化:   Antigen affinity purification
种属反应性:   Human, Mouse, Rat
成分:   PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
研究领域:   Epigenetics and Nuclear Signaling, Stem Cells, Developmental Biology
储存和运输:   Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human thyroid cancer tissue using 221531(YBX1 Antibody) at a dilution of 1/25(Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human thyroid cancer tissue is first treated with the synthetic peptide and then with 221531(Anti-YBX1 Antibody) at dilution 1/25.

The image on the left is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using 221531(Anti-YBX1 Antibody) at a dilution of 1/25.

In comparision with the IHC on the left, the same paraffin-embedded Human cervical cancer tissue is first treated with synthetic peptide and then with D263167(Anti-YBX1 Antibody) at dilution 1/25.
           引用文献