武汉费斯德生物科技有限公司, NewEast Biosciences 中国办事处

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Cdc42 Chicken

Anti-Cdc42 Chicken Polyclonal Antibody
5/5

¥2,600.00

货号:21019

规格: 100 微升

库存状态:In Stock

           产品描述          
产品名称:   Chicken Cdc42
货号:   21019
基因符号:   CDC42
描述:   Cdc42 Chicken 兔多抗
背景:   Small GTPases are a super-family of cellular signaling regulators. Cdc42 belongs to the Rho sub-family of GTPases that regulate cell motility, cell division, and gene transcription. GTP binding increases the activity of Cdc42, and the hydrolysis of GTP to GDP renders it inactive. GTP hydrolysis is aided by GTPase activating proteins (GAPs), while exchange of GDP for GTP is facilitated by guanine nucleotide exchange factors (GEFs).
免疫原 :   Recombinant full length Cdc42 蛋白
经过测试的应用:   ELISA, WB, IHC
推荐稀释比:   
ELISA: 1:100-1:5000
WB: 1:100-1:1000
IHC: 1:100-1:1000
Concentration:   1 mg/ml
种属反应性:   Chicken
形式:   Liquid
克隆性:  Polyclonal
亚型:   IgY
纯化:   Purified from egg yolk
成分:   PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol
种属反应性:   Cdc42 antibody recognizes Cdc42 from vertebrates.
储存条件:   Store at -20°C. Avoid repeated freezing and thawing

蛋白质印迹:   

Western blot analysis of Cdc42 proteins.

HepG whole-cell lysate was used for Western blot with the chicken polyclonal Anti-Cdc42 antibody (cat # 21019).

           引用文献          
1.  Vibrio parahaemolyticus Effector Proteins Suppress Inflammasome Activation by Interfering with Host Autophagy Signaling
PLoS Pathog. 2013 Jan;9(1):e1003142
2.  Interferon gamma induces actin polymerization, Rac1 activation and down regulates phagocytosis in human monocytic cells
Cytokine. 2012 Jan;57(1):158-68
3.  Invadopodia and rolling-type motility are specific features of highly invasive p190bcr-abl leukemic cells
European Journal of Cell Biology Volume 91, Issues 11–12, November–December 2012, Pages 978–987
4.  Epithelial junction formation requires confinement of Cdc42 activity by a novel SH3BP1 complex
J Cell Biol. 2012 Aug 20;198(4):677-93
5.  Polarized migration of lymphatic endothelial cells is critically dependent on podoplanin regulation of Cdc42
Am J Physiol Lung Cell Mol Physiol. 2011 Jan;300(1):L32-42
6.  The Aarskog-Scott Syndrome Protein Fgd1 Regulates Podosome Formation and Extracellular Matrix Remodeling in Transforming Growth Factor beta-Stimulated Aortic Endothelial Cells
Mol Cell Biol. 2011 Nov;31(22):4430-41
7.  MMP-9 and CXCL8/IL-8 Are Potential Therapeutic Targets in Epidermolysis Bullosa Simplex
PLoS One. 2013 Jul 19;8(7):e70123
8.  p21-Activated Kinase (PAK) Regulates Cytoskeletal Reorganization and Directional Migration in Human Neutrophils
PLoS One. 2013 Sep 3;8(9):e73063
9.  The Cdc42 Guanine Nucleotide Exchange Factor FGD6 Coordinates Cell Polarity and Endosomal Membrane Recycling in Osteoclasts
J Biol Chem. 2014 Jun 27;289(26):18347-59
10.  Cdc42 Inhibitor and Uses Thereof
United States Patent Application 20140194451
11.  The α4 Nicotinic Receptor Promotes CD4+ T-Cell Proliferation and a Helper T-Cell Immune Response
Molecular Pharmacology January 2014 vol. 85 no. 1 50-61